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  Causes of AMD

Causes of age-related macular degeneration

The exact cause of age-related macular degeneration still eludes the ophthalmologists. But certain risk factors have been identified.

Aging: Aging process is believed to be the main reason for AMD. It is estimated that about 10% of the total population of the world in the age group of 66 to 74 years is suffering from the disease. The percentage of people getting affected by AMD increases as the aging process increases.

Smoking: Researches in macular degeneration have found that smoking increases the risk of age-related macular degeneration.

Gender: Women are more prone to AMD than men.

Race: The disease is found more in white people than in black people.

Family history: The chances of a person developing AMD is high if the person’s family has a history of age-related macular degeneration.

Color of the eye: People with blue eyes are more prone to AMD. This is because blue eyes have less protective pigment which neutralizes the ultraviolet light effect.

Diet: Researches have identified high fat intake as a major reason for the development of AMD.

Other diseases leading to age-related macular degeneration: People suffering from hypertension, obesity and high cholesterol can develop age-related macular degeneration.

Sunlight: It is believed that over exposure of the eyes to sun increases the risk of AMD. But this continues to be a debated issue as certain studies does not agree with the view point.

Latest researches point that the accumulation of pro-oxidant melanin oligomers within lysosomes of retinal pigment epithelium is the cause of AMD. As there is a constant increase annually in the number of patients suffering age-related macular degeneration, more and more researches are being conducted to determine the exact cause of the disease.
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